Rescuers in China and Nepal are searching for about 1,300 people who are missing after a flash flood hit the two countries.At least 359 people have died in Nepal, with three confirmed deaths in China. We'll hear from both countries.Also in the programme: Ratko Mladic, the former Bosnian Serb commander who was convicted of genocide, has died in prison - we hear from the journalist Allan Little who covered him for the BBC and Hasan Hasanovic, a survivor of Srebrenica massacre; why some species of bats are able to live so long; and we'll remember the Japanese avant-garde artist Yayoi Kusama, whose struggles with her mental health fuelled her work:(Photo shows flood survivors in Devighat Village, Nuwakot district, Nepal on 27 August 2026. Credit: Narendra Shrestha/EPA)

The social media giant Meta, which owns Facebook and Instagram, has agreed to restrict American teenagers’ use of its platforms as part of an $18bn settlement with states that accused it of harming children. We hear from a former Meta insider. Also on the programme: how climate change is increasing the likelihood of avalanches and flooding in the Himalayas; and we look back on the life of Rocky Horror Picture Show star Tim Curry.(Photo: The Meta logo is displayed on a mobile phone in Liverpool, Britain, 09 June 2026. Credit: ADAM VAUGHAN/EPA/Shutterstock)

Hundreds of people are missing, including at least 291 foreign tourists, after a flash flood on the Nepal-Tibet border.At least 18 people are confirmed dead in Nepal; Chinese state media is also reporting "major casualties" in Tibet, which is controlled by China. We'll hear how this incident is affecting people on the ground.Also in the programme: Tragedy at one of Pakistan's main hospitals, where at least 14 newborn babies have been killed in a fire; new research shows a new shingles vaccine can lower the risk of heart disease; and we'll reflect on the wisdom and humour of country music icon Dolly Parton, who died yesterday. (Photo shows a satellite image of the valleys near the Nepal-China border, after the devastating floods on26 August 2026 Planet Labs PBC/Reuters)

The country music legend Dolly Parton has died at the age of 80 in Nashville, Tennessee. In a seven-decade career, she won 10 Grammy awards, sold more than 100 million records worldwide, and wrote in excess of 3,000 songs. We'll be looking back at her life and legacy.Also in the programme: the United Nations and the Red Cross have called for urgent negotiations to restrict the use of autonomous weapons; and why the Indian government is sending onions across the country.(Photo: The American country music star, Dolly Parton, performs on the Pyramid Stage during the Glastonbury Festival June 29, 2014. Reuters/Cathal McNaughton.)

China has vowed to protect its interests after the US announced plans to widen economic sanctions against Iran and its trading partners, which include Beijing. Will China scupper the squeeze on Iran?Also in the programme: the UN and Red Cross call for urgent new laws to police fully autonomous weapons, an at-home test kit for cervical cancer. and can Australia keep AI out of music?(Photo: US Treasury Secretary Scott Bessent during a press conference to outline further sanctions against Iran,in Washington DC on 24 August 2026. Credit: Evelyn Hockstein/Reuters)

The US treasury secretary, Scott Bessent, has unveiled a wave of sanctions aimed at isolating Iran's economy and says that other countries will be pressured to comply. But will the US deliver on its threats?Also in the programme: a group of cricket legends urges Pakistan to give the former prime minister, Imran Khan, proper medical care; and the edible cookie made from plastic waste. (Photo: US Treasury Secretary Scott Bessent speaks during a press conference to outline further sanctions against Iran in Washington, August 24, 2026. Credit: Reuters/Evelyn Hockstein.)

The US treasury secretary has threatened Iran with "the single greatest financial offensive ever", claiming the US-Israel war with Iran was "entering its endgame".Scott Bessent said the US would sever all economic ties with the country in "an economic D-Day" and that any nation partnering with Iran financially would also be isolated. Will it work?Also in the programme: A blueprint for new weapons for Ukraine; the Taliban answers questions about its treatment of women; and the rare British bird on the rise.(Photo shows US Secretary of Treasury Scott Bessent speaks to reporters in Washington, DC, USA on 20 August 2026. Credit: Shawn Thew/EPA)

Iran’s currency, the rial, has hit a record low, trading at over 2 million rials to the dollar on unofficial markets. The devaluation comes a day before the United States is due to impose what US Treasury Secretary Scott Bessant described as “the toughest sanctions in history” on Tehran. Iran was struggling financially even before the start of its ongoing conflict with the US and Israel, nearly six months ago.Also in the programme: Ukrainian President Volodymyr Zelensky warns against holding wartime elections, following repeated calls from his sacked defence minister to hold a nationwide vote; Syria’s foreign minister says he expects peace talks with Israel to resume soon; and we hear from the director of London’s Natural History Museum, where a gallery which has remained hidden from view since World War Two is about to reopen.(Photo: Iranian woman buys vegetables at a street market in Tehran, Iran, 22 August 2026. Credit: Abedin Taherkenareh/EPA/Shutterstock)

Ukraine's popular former defence minister Mykhailo Fedorov tells the BBC he still wants nationwide elections, despite his country being at war. We hear a response from a supporter of President Zelensky. Also in the programme: how the Trump White House has turned one of the US's big sporting occasions into a political event; and diplomatic conflict between the UK and Russia, as Moscow apparently withdraws its ambassador from London.(IMAGE: Mykhailo Fedorov, who was at the time Ukraine's minister of defence, speaks at a press conference, amid Russia's attack on Ukraine, in Kyiv, Ukraine, July 1, 2026 / CREDIT: REUTERS/Alina Smutko/File Photo)

Canada's prime minister, Mark Carney, has confirmed he'll impose retaliatory tariffs on the United States next month, saying trade talks collapsed because Washington made unacceptable demands.Also on the programme, the editor-in-chief and a reporter from the US military newspaper Stars and Stripes have been fired for 'insubordination', South Korea's first container ship to trial the much shorter and safer route to Europe via the Arctic has begun its journey, and a look at the event dubbed the "Robot Olympics".Canada’s Prime Minister Mark Carney speaks with the news media after he suspended trade negotiations with the United States, in Ottawa, Ontario, Canada August 22, 2026. REUTERS/Chris Tanouye