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The seven-night cruise ended in Miami on Saturday after making three stops in the Caribbean. More than 6,000 people were on the ship, which required testing and those 12 and over to be vaccinated.

President Biden is expected to address the surge in omicron cases, but is his administration's response fast and sufficient enough to meet what could be the most challenging month yet in the pandemic?

The Biden administration is putting a quarter of a billion dollars into a new national suicide prevention line. But some say that's not enough to build the infrastructure that's needed.

NPR's Ari Shapiro speaks with California Attorney General Rob Bonta about a recent spate of "smash and grab" incidents at California retailers.

The Netherlands has gone into a strict lockdown over the Christmas and New Year to try to contain the omicron variant. It's the country third lockdown since the beginning of the pandemic.

In a rare reversal, the Justice Department said the prison system has discretion to allow people released to home confinement during the pandemic to remain free.

Opioids can kill because they reduce breathing along with pain. Now brain scientists have made a discovery that could lead to potent pain drugs that don't affect breathing.

Photographers from NPR's member stations across the country share memorable images from 2021. There are stories that document grief to ones that spread joy in a tumultuous year.

Joseph Moore wore a wire for the FBI under his white robe.

NASA's James Webb Space Telescope is waiting at its launch site, after years of repeated delays and cost overruns. At one point, the giant new observatory was threatened with cancellation.