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If Dave Isay has learned one thing from editing his new book of StoryCorps conversations it's this: "No one should ever, ever give up hope on love," he says. "It seems like it's not in the cards for people, and then it just sneaks up behind you."

When Americans traveled by stagecoach, they had to worry about rocks, rattlesnakes, robbers and other varmints. But I wonder if there weren't fewer passenger complaints.

Talk of the Nation listeners wrote to the show to share their insights on previous show topics, including genetic testing, affirmative action, the source and practice of patience, and interracial marriage.

Overcrowded prisons already coping with budget pressures face a new challenge: The growing needs of an aging inmate population. With limited state budgets, prison setups, and facilities, prison officials are trying new ways to provide care and, in some cases, opting to release inmates early.

The same folks who have sponsored essay contests about the costs of medical care have a subversive video out that puts health care charges and billing in a pretty embarrassing light. A big bill from the Hotel Hospital.

Finding the Higgs boson would confirm a key part of physics' Standard Model.

Brazil moved toward relaxing its strict ban on alcohol at soccer games Tuesday, responding to World Cup organizers' concerns. Soccer's governing body is pushing for the change so it can make Budweiser the "Official Beer of the FIFA World Cup" when Brazil hosts the event in 2014.

Former President Ronald Reagan would surely be pleased to know that many of his legacies remain vital in 2012, from campaign pledges to lower taxes to ketchup's classification as a vegetable. Reagan is also responsible for a lesser-known contribution to American food culture: National Frozen Food Day.

When the inhalable caffeine product, known as AeroShot, hit college campus stores back in January, it caused a buzz, not all of it euphoric. Now the U.S. Food and Drug Administration has warned the company that makes it about the labeling and safety of its product.

As his national profile has risen, the first-term senator from Florida has become a target for Democrats and advocacy groups who say he doesn't represent Latino voters. In Miami last week, a dozen young Hispanic men and women gathered outside Rubio's office chanting, "Rubio: Latino or Tea Partino?"