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Scientists at Virginia Tech discover large virus in algae

Two hands hold three sample containers with algae cells inside a laboratory.
Roxy Todd
/
Radio IQ
Frank Aylward, associate professor in the department of biological sciences at Virginia Tech and PhD candidate Paula Erazo hold samples of the green algae they analyzed for their study.

Scientists in Blacksburg have discovered a large, previously unseen virus inside algae. The virus poses no risk to human health but the discovery reveals just how adaptive viruses can be, said Frank Aylward, associate professor in the department of biological sciences at Virginia Tech and one of the researchers on the study.

“There are lots of viruses out there in the biosphere. If you go out in the duck pond right now, you would find trillions and trillions of viruses in just a small volume of water,” Aylward said. “Viruses are by far more abundant by far than any other life form on the planet.”

He and PhD student, Paula Erazo, the lead researcher on the study, suspected they might be able to find a virus inside a green algae called Chlamydomonas reinhardtii, a species that has been heavily studied for over 70 years.

Hands hold two samples of algae inside cylindrical test tubes. Person holding them is wearing a t-shirt with an illustration of a frog.
Roxy Todd
/
RadioIQ
PhD student, Paula Erazo, holds two samples of algae.

They bought a 30-year-old lab sample of the algae and began looking at it with genome sequencing technology.

“And this particular strain had been in culture for 30 years,” Aylward explained.

They discovered a virus that had been there, inside the algae, undetected for decades.

“We could definitely see that there was a virus inserted there,” Erazo said. “Which is something we couldn’t see before because the technology wasn’t as advanced.”

“What’s unusual about this is that the cultures look perfectly healthy. There’s no sign that there is any kind of viral infection going on,” Aylward said.

Aylward said the virus is the largest of its kind ever discovered. It inserts its own genome into the DNA of the host algae, similar to how HIV affects humans.

“It was not known that this could happen in viruses that are quite so big as this one,” Aylward said.

Aylward said future research of the virus may teach scientists more about gene editing techniques.

Their study was published in the journal “Science” and Erazo presented their findings at a conference in France, where she won an award for the best presentation by a graduate student.

A hand holds a glass beaker with water and green algae
Roxy Todd
More green algae being studied inside the Aylward lab at Virginia Tech

This report, provided by Virginia Public Radio, was made possible with support from the Virginia Education Association.

Updated: May 15, 2025 at 12:53 PM EDT
Editor's Note: Radio IQ is a service of Virginia Tech.
Roxy Todd is Radio IQ's New River Valley Bureau Chief.